TCMSP is a unique systems pharmacology platform of Chinese herbal medicines that captures the relationships between drugs, targets and diseases. The database includes chemicals, targets and drug-target networks, and associated drug-target-disease networks, as well as pharmacokinetic properties for natural compounds involving oral bioavailability, drug-likeness,intestinal epithelial permeability, blood-brain-barrier, aqueous solubility and etc. This breakthrough has sparked a new interest in the search of candidate drugs in various types of traditional Chinese herbs.
The authors are grateful to the TTD (Therapeutic Target Database), PharmGKB and PubChem database. The network viewer in our website is based on CytoscapeWeb,an interactive web-based network browser. It is freely available at http://cytoscapeweb.cytoscape.org/ .
Please Cite: Jinlong Ru; Peng Li; Jinan Wang; Wei Zhou; Bohui Li; Chao Huang; Pidong Li; Zihu Guo; Weiyang Tao; Yinfeng Yang; Xue Xu; Yan Li; Yonghua Wang; Ling Yang. TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. J Cheminformatics. 2014 Apr 16;6(1):13.
License Agreement: TCMSP is made available under the Open Database License: http://opendatacommons.org/licenses/odbl/1.0/. Any rights in individual contents of the database are licensed under the Database Contents License: http://opendatacommons.org/licenses/dbcl/1.0/.
Disclaimer: The content of TCMSP is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.